Journal article

Lateralization of the startle reflex circuit in humans: An examination with monaural probes following unilateral temporal lobe resection

JWL Kettle, DG Andrewes, NB Allen

BEHAVIORAL NEUROSCIENCE | AMER PSYCHOLOGICAL ASSOC | Published : 2006

Abstract

Startle reflex (SR) modulation elicited by monaural probes during affective picture viewing was investigated in patients following left temporal lobectomy (LTL; n = 8) and right temporal lobectomy (RTL; n = 10) and in controls (n = 18). All patients had undergone anteromedial temporal lobe (ATL) resection. LTL participants exhibited attenuated overall SR magnitude. Affective SR modulation in controls was significant for left ear probes, at both eyes, but not for right ear probes. RTL but not LTL participants displayed significant startle attenuation during pleasant picture viewing. Results suggest that monaural startle probes primarily activate structures in the ipsilateral ATL and that the ..

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