Evaluation of four proposed bleeding criteria for the onset of late menopausal transition

Abstract

Context: The current criterion for onset of late menopausal transition is amenorrhea of 90 d or more. The Stages of Reproductive Aging Workshop proposed alternative criteria based on a shorter period of amenorrhea. Empirical data comparing proposed criteria are not available. Objective: This paper evaluates the several bleeding criteria that served as the basis of these recommendations. The goal was to provide empirically based guidance regarding which bleeding criterion may be optimal for widespread application in clinical and research settings. Design/Setting: The study used prospective menstrual calendar data from four community and population-based cohort studies: TREMIN, Melbourne Women..