Journal article
Human transmissible spongiform encephalopathies in eleven countries: Diagnostic pattern across time, 1993-2002
J De Pedro-Cuesta, M Glatzel, J Almazán, K Stoeck, V Mellina, M Puopolo, M Pocchiari, I Zerr, HA Kretszchmar, JP Brandel, N Delasnerie-Lauprêtre, A Alpérovitch, C Van Duijn, P Sanchez-Juan, S Collins, V Lewis, GH Jansen, MB Coulthart, E Gelpi, H Budka Show all
BMC Public Health | BMC | Published : 2006
Abstract
Background: The objective of this study was to describe the diagnostic panorama of human transmissible spongiform encephalopathies across 11 countries. Methods: From data collected for surveillance purposes, we describe annual proportions of deaths due to different human transmissible spongiform encephalopathies in eleven EUROCJD-consortium countries over the period 1993-2002, as well as variations in the use of diagnostic tests. Using logistic models we quantified international differences and changes across time. Results: In general, pre-mortem use of diagnostic investigations increased with time. International differences in pathological confirmation of sporadic Creutzfeldt-Jakob disease,..
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