Journal article

Retinal vascular caliber and risk of retinopathy in young patients with type 1 diabetes

Ekaterina Alibrahim, Kim C Donaghue, Sophie Rogers, Stephen Hing, Alicia J Jenkins, Albert Chan, Tien Y Wong



OBJECTIVE: To examine the relationship between retinal vascular caliber and incident retinopathy in children and adolescents with type 1 diabetes mellitus. DESIGN: Hospital-based case-control study with prospective outcomes. PARTICIPANTS: Cases and controls were selected from a cohort of children and adolescents 12 to 20 years old with type 1 diabetes followed up at a tertiary diabetes clinic. Cases were patients who developed incident diabetic retinopathy (n = 166) after at least 1 year of follow-up (> or =2 clinic visits), and controls were patients who had not developed retinopathy (n = 165) after > or =2 years of follow-up (> or =3 clinic visits). Baseline retinal photographs of cases an..

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