Retinal Vascular Caliber and Risk of Retinopathy in Young Patients with Type 1 Diabetes

Abstract

Objective: To examine the relationship between retinal vascular caliber and incident retinopathy in children and adolescents with type 1 diabetes mellitus. Design: Hospital-based case-control study with prospective outcomes. Participants: Cases and controls were selected from a cohort of children and adolescents 12 to 20 years old with type 1 diabetes followed up at a tertiary diabetes clinic. Cases were patients who developed incident diabetic retinopathy (n = 166) after at least 1 year of follow-up (≥2 clinic visits), and controls were patients who had not developed retinopathy (n = 165) after ≥2 years of follow-up (≥3 clinic visits). Baseline retinal photographs of cases and controls were..