Journal article

Odontoblast dysfunction in osteogenesis imperfecta: An LM, SEM, and ultrastructural study

RK Hall, MC Maniere, J Palamara, J Hemmerle

CONNECTIVE TISSUE RESEARCH | TAYLOR & FRANCIS LTD | Published : 2002

Abstract

The inherited dentin defect dentinogenesis imperfecta (DI), while clinically obvious in osteogenesis imperfecta (OI) Types IB and IC, II, III, and IVB, is now thought to be present in all children with OI, in a continuum from minimal to severe dentin pathology. This collaborative study further clarifies the structural and ultrastructural dentin changes in the teeth of OI children with clinically obvious DI, and attempts to explain these in terms of odontoblast dysfunction. Collaborative studies were carried out in Melbourne, Australia, and Strasbourg, France, using light and polarized-light microscopy, scanning and transmission electron microscopy (SEM, TEM), selected-area diffraction (SAD),..

View full abstract