Journal article

Improved antigen binding by a CD20-specific single-chain antibody fragment with a mutation in CDRH1

PJ Adamson, DJ Millard, AW Hohmann, C Mavrangelos, PJ Macardle, G Pilkington, TD Mulhern, TF Tedder, H Zola, IC Nicholson

Molecular Immunology | PERGAMON-ELSEVIER SCIENCE LTD | Published : 2006

DOI: 10.1016/j.molimm.2005.04.016

University of Melbourne Researchers

Grants

Citation metrics

2Web of Science
2Scopus
2Dimensions

Keywords

Antigen-Antibody Reactions
Immunoglobulin Mutation
Antigens, Cd20
Models, Molecular
Expression
Immunology
Human B-Cells
Fusion Protein
Complementarity Determining Regions
Rituximab
Life Sciences & Biomedicine
Immunoglobulin Fragments
Therapy
Complementarity Determining Region
Biochemistry & Molecular Biology
Amino Acid Sequence
Mouse
Mutation
Single-Chain Antibody Fv Fragment
Immunoglobulin Heavy Chains
Humans
Immunoglobulin Variable Region
Phage Display
Monoclonal-Antibodies
In-Vivo
Hybridomas
Science & Technology
Cd20