Journal article

A national study on lymph node retrieval in resectional surgery for colorectal cancer

Paris P Tekkis, Jason J Smith, Alexander G Heriot, Ara W Darzi, Michael R Thompson, Jeffrey D Stamatakis

DISEASES OF THE COLON & RECTUM | LIPPINCOTT WILLIAMS & WILKINS | Published : 2006

Abstract

PURPOSE: This study was designed to develop a mathematical model for predicting the number of lymph nodes harvested in bowel cancer resection specimens based on the current clinical practice in the United Kingdom. METHODS: Prospective clinical data were collected from 8,409 newly diagnosed bowel cancer patients presenting to 79 hospitals in Great Britain and Ireland during a variable 12-month period from 2000 to 2002. A two-level hierarchical regression model was used to identify predictors for lymph node harvest. The model was internally validated by comparing observed and model predicted lymph node harvest for patient subgroups. RESULTS: Inclusion criteria were satisfied by 5,164 patients...

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