Journal article

Construction of the femoral neck during growth determines its strength in old age

Roger MD Zebaze, Anthony Jones, Mark Knackstedt, Ghassan Maalouf, Ego Seeman

JOURNAL OF BONE AND MINERAL RESEARCH | WILEY | Published : 2007

Abstract

UNLABELLED: Study of the design of the FN in vivo in 697 women and in vitro in 200 cross-sections of different sizes and shapes along each of 13 FN specimens revealed that strength in old age was largely achieved during growth by differences in the distribution rather than the amount of bone material in a given FN cross-section from individual to individual. INTRODUCTION: We studied the design of the femoral neck (FN) to gain insight into the structural basis of FN strength in adulthood and FN fragility in old age. MATERIALS AND METHODS: Studies in vivo were performed using densitometry in 697 women and in vitro using high-resolution microCT and direct measurements in 13 pairs of postmortem ..

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University of Melbourne Researchers