Journal article

Management of tunnel fungal infection with voriconazole

Vishal Jhanji, Namrata Sharma, Rashim Mannan, Jeewan S Titiyal, Rasik B Vajpayee

JOURNAL OF CATARACT AND REFRACTIVE SURGERY | ELSEVIER SCIENCE INC | Published : 2007

Abstract

A 59-year-old woman presented 1 month after cataract surgery in the right eye with a stromal infiltrate at the site of the cataract surgery wound. The visual acuity was perception of light with accurate projection. Corneal scraping of the infiltrate revealed septate hyphae. There was no response to 6 weeks of therapy with topical fortified antibiotic agents and topical antifungal therapy in the form of natamycin 5%, amphotericin B 0.15%, and intracameral amphotericin B. The patient was started on oral voriconazole 200 mg twice daily and topical voriconazole 1% every hour, and resolution of the ulcer was noted within 3 days. At the 4-month follow-up, a visual acuity of 20/60 was achieved, wit..

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