Journal article

The temporal sequence of allergic sensitization and onset of infantile eczema

AJ Lowe, MJ Abramson, CS Hosking, JB Carlin, CM Bennett, SC Dharmage, DJ Hill

CLINICAL AND EXPERIMENTAL ALLERGY | BLACKWELL PUBLISHING | Published : 2007

Abstract

BACKGROUND: Eczema is commonly associated with sensitization in infants, but the causative role of sensitization in the development of eczema has been questioned. OBJECTIVE: To determine if allergic sensitization increases the risk of developing eczema, or alternatively, if eczema increases the risk of developing allergic sensitization. METHODS: We used data from the Melbourne Atopy Cohort Study, a prospective birth cohort of 552 infants with a family history of atopic disease. The main outcomes were risk of developing eczema from 6 months to 7 years of age in asymptomatic infants; and risk of developing sensitization, as measured by skin prick tests to milk, egg white, peanut, house dust mi..

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