Journal article

The Liverpool adverse events profile: Relation to AED use and mood

Rosemary June Panelli, Christine Kilpatrick, Susan M Moore, Zelko Matkovic, Wendyl J D'Souza, Terence J O'Brien

EPILEPSIA | WILEY | Published : 2007

Abstract

PURPOSE: The Liverpool Adverse Events Profile (LAEP) is used as a systematic measure of adverse effects from antiepileptic drugs (AEDs). This study evaluated LAEP in newly diagnosed seizure patients, and examined the relation between LAEP, anxiety, and depression. METHODS: Seizure patients seen in the two First Seizure Clinics were categorized into group A (AEDs commenced after assessment), group B (AEDs commenced before assessment), and group C (no AEDs). LAEP and the Hospital Anxiety and Depression Scale (HADS) were completed at baseline (n=164) and 3 months (n=103). Each LAEP symptom was assessed for baseline frequency, 3-month frequency, and frequency change over a 3-month period. Global..

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