Journal article

Outcomes for Mycobacterium ulcerans infection with combined surgery and antibiotic therapy: findings from a south-eastern Australian case series

Daniel P O'Brien, Andrew J Hughes, Allen C Cheng, Margaret J Henry, Peter Callan, Anthony McDonald, Ian Holten, Mike Birrell, John M Sowerby, Paul DR Johnson, Eugene Athan

MEDICAL JOURNAL OF AUSTRALIA | WILEY | Published : 2007

Abstract

OBJECTIVE: To describe the effect of antibiotics on outcomes of treatment for Buruli or Bairnsdale ulcer (BU) in patients on the Bellarine Peninsula in south-eastern Australia. DESIGN: Observational, non-randomised study with data collected prospectively or through medical record review. PATIENTS AND SETTING: All 40 patients with BU managed by staff of Barwon Health's Geelong Hospital (a public, secondary-level hospital) between 1 January 1998 and 31 December 2004. MAIN OUTCOME MEASURES: Epidemiology, clinical presentation, diagnosis, treatment and clinical outcomes. RESULTS: There were 59 treatment episodes; 29 involved surgery alone, 26 surgery plus antibiotics, and four antibiotics alone...

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