Journal article

Memory complaints in nondemented men predict future pathologic diagnosis of Alzheimer disease

AF Jorm, KH Masaki, DG Davis, J Hardman, J Nelson, WR Markesbery, H Petrovitch, GW Ross, LR White

Neurology | LIPPINCOTT WILLIAMS & WILKINS | Published : 2004

Abstract

The validity of memory complaints as a predictor of Alzheimer disease (AD) was assessed in 237 Japanese-American men autopsied at ages 74 to 97 years. These men were free of dementia at the time memory complaints were assessed 1 to 11 years earlier. Memory complaints were found to predict the neuropathologic diagnosis of AD after adjusting for age, time to death, education, depression, and cognitive functioning.

University of Melbourne Researchers