Journal article

Digital blood flow and plasma endothelin concentration in clinically endotoxemic horses

NJ Menzies-Gow, SR Bailey, K Stevens, L Katz, J Elliott, CM Marr

AMERICAN JOURNAL OF VETERINARY RESEARCH | AMER VETERINARY MEDICAL ASSOC | Published : 2005

Abstract

OBJECTIVE: To measure plasma endothelin-1 (ET-1) concentrations and digital blood flow in clinically endotoxemic horses. ANIMALS: 36 adult horses that underwent emergency celiotomy for primary gastrointestinal tract disease. PROCEDURE: On days 2 and 5 following surgery, Doppler ultrasonographic digital arterial blood flow measurements were obtained. Hematologic and biochemical analyses were performed, and plasma concentrations of ET-1 and endotoxin (lipopolysaccharide) were determined. A scoring system based on 9 clinical variables was used to assign horses to group B (quartile with greatest cumulative score) or group A (remaining 3 quartiles). Follow-up at 2.5 years was obtained by telephon..

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University of Melbourne Researchers