Journal article

Genetic aspects of hearing loss

HH Dahl, S Manji, M De Silva, M Peverelli, M Hildebrand

Acoustics Australia | Published : 2006

Abstract

Genes mediate the workings of cells, organs and organisms. Since normal hearing is dependent on highly specialised structures and cellular functions it is not surprising that many genes - as well as environmental factors - affect this complex process. A number of genes have been identified to date that have added to our knowledge of the molecular aspects of hearing. Mutations, or changes, in these genes cause deafness or hearing impairment demonstrating that these genes are essential for normal hearing function. Despite the advances we have made in the discovery of "deafness" genes, little is known about the genes that determine susceptibility to noise-induced deafness, ototoxic hearing loss..

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