Journal article

Recombinant factor VIIa in massive postpartum haemorrhage

D Karalapillai, P Popham

INTERNATIONAL JOURNAL OF OBSTETRIC ANESTHESIA | ELSEVIER SCI LTD | Published : 2007

Abstract

Massive postpartum haemorrhage is a major cause of maternal and fetal morbidity and mortality. Management mainstays include transfusion therapy, uterotonic agents and surgery. The "off label" use of recombinant activated factor VII appears to have an evolving role in the management of massive postpartum haemorrhage refractory to conventional treatments. The current literature is reviewed.