Journal article

Postpartum thiamine deficiency in a Karen displaced population

R McGready, JA Simpson, T Cho, L Dubowitz, S Changbumrung, V Bohm, RG Munger, HE Sauberlich, NJ White, F Nosten

AMERICAN JOURNAL OF CLINICAL NUTRITION | AMER SOC CLINICAL NUTRITION | Published : 2001

Abstract

BACKGROUND: Before its recognition, infantile beriberi was the leading cause of infant death in camps for displaced persons of the Karen ethnic minority on Thailand's western border. OBJECTIVE: This study aimed to document thiamine status in the peripartum period to examine the current supplementation program and the correlation between the clinical manifestations of thiamine deficiency and a biochemical measure of thiamine status. DESIGN: Women were enrolled prospectively at 30 wk of gestation and were followed up weekly until delivery and at 3 mo postpartum. Thiamine supplementation during pregnancy was based on patient symptoms. RESULTS: At 3 mo postpartum, thiamine deficiency reflected b..

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