Journal article

Apolipoprotein E4 forms a molten globule - A potential basis for its association with disease

JA Morrow, DM Hatters, B Lu, P Hochtl, KA Oberg, B Rupp, KH Weisgraber

Journal of Biological Chemistry | AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC | Published : 2002

DOI: 10.1074/jbc.M204898200

Grants

Awarded by NINDS NIH HHS

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Keywords

Neurite Outgrowth
Spectroscopy, Fourier Transform Infrared
Science & Technology
Apolipoprotein E3
Apolipoproteins E
Life Sciences & Biomedicine
Urea
Protein Structure, Secondary
Conformational-Changes
Hydrogen-Ion Concentration
Protein Conformation
Apolipoprotein E4
Lipid-Binding
Alzheimers-Disease
Dimyristoylphosphatidylcholine
Biochemistry & Molecular Biology
Aqueous-Solution
E Isoforms
Pepsin a
Peptide Fragments
Receptor-Related Protein
Amino-Terminal Domain
Models, Molecular
Transform Infrared-Spectroscopy
Protein Denaturation
Humans
Protein Isoforms
Myocardial-Infarction