Improvement in Protection against Adenocarcinoma of the Cervix Resulting from Participation in Cervical Screening

Abstract

BACKGROUND. The incidence of adenocarcinoma of the cervix did not decline in Western countries in the 1970s and 1980s despite the availability and use of cervical cytologic screening. The impact of improved endocervical sampling and better recognition of the cytologic precursors to adenocarcinoma during the 1990s in reducing the risk of adenocarcinoma is currently unknown. METHODS. Using records from a statewide registry, the authors compared the screening histories of 160 women with adenocarcinoma (33 microinvasive cases and 127 invasive cases) who were diagnosed between 1995 and 2001 with the screening histories of 640 control women in a matched case-control study. RESULTS. A decreased ris..