Journal article

Factors contributing to anemia after uncomplicated falciparum malaria

RN Price, JA Simpson, F Nosten, C Luxemburger, L Hkirjaroen, F Ter Kuile, T Chongsuphajaisiddhi, NJ White

American Journal of Tropical Medicine and Hygiene | AMER SOC TROP MED & HYGIENE | Published : 2001

Abstract

The factors contributing to anemia in falciparum malaria were characterized in 4,007 prospectively studied patients on the western border of Thailand. Of these, 727 patients (18%) presented with anemia (haematocrit < 30%), and 1% (55 of 5,253) required blood transfusion. The following were found to be independent risk factors for anemia at admission: age 2 days) before admission, and pure Plasmodium falciparum infections rather than mixed P. falciparum and Plasmodium vivax infections. The mean maximum fractional fall in hematocrit after antimalarial treatment was 14.1% of the baseline value (95% confidence interval [CI], 13.6-14.6). This reduction was significantly greater in young children..

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