Journal article

Tropisetron modulation of the glycine receptor: femtomolar potentiation and a molecular determinant of inhibition

Zhe Yang, Agnieszka Ney, Brett A Cromer, Hooi-Li Ng ng, Michael W Parker, Joseph W Lynch

Journal of Neurochemistry | WILEY | Published : 2007

DOI: 10.1111/j.1471-4159.2006.04242.x

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Keywords

Dose-Response Relationship, Drug
Tropeine
Al Subunit
Neural Inhibition
Cys-Loop Receptor
Ion Channel Gating
Ligand-Gated Ion Channel
Protein Structure, Tertiary
Life Sciences & Biomedicine
Receptors, Glycine
Identification
Channel
Humans
Femtomolar
Mutation
Binding Site
Neurosciences
Antagonists
Site
Chloride Channels
Ligands
Patch-Clamp Techniques
Molecular Structure and Function
Drug Interactions
Cell Membrane
Responses
Ligand-Binding Domain
Indoles
Tropisetron
Glycine
Models, Molecular
Cell Line
5-Ht3 Receptor Antagonist
Nitrogen
Biochemistry & Molecular Biology
Rat Spinal Neurons
Neurosciences & Neurology
Allosteric Modulation
Serotonin Antagonists
Protein Subunits
Science & Technology
5-Ht3 Receptor
Binding Sites