Journal article

Temporal relationship between gastrointestinal protein loss, gastric ulceration or erosion, and strenuous exercise in racing Alaskan sled dogs

Michael Davis, Michael Willard, Katherine Williamson, Chris Royer, Mark Payton, Jorg M Steiner, Kenneth Hinchcliff, Erica McKenzie, Stuart Nelson

JOURNAL OF VETERINARY INTERNAL MEDICINE | WILEY | Published : 2006

Abstract

BACKGROUND: Alterations in the appearance and function of gastrointestinal mucosa are common after strenuous exercise. However, the duration of exercise required to alter the gastrointestinal mucosa has not been reported. HYPOTHESIS: We used 42 sled dogs to test the hypothesis that the magnitude of exercise-induced gastrointestinal mucosal dysfunction is related to exercise duration. ANIMALS: Six dogs served as conditioned controls, and the remaining dogs were randomly chosen for examination after 1-5 consecutive days of running at 100 miles/d. METHODS: Gastroduodenoscopy and measurement of gastric permeability were performed 24 hours after cessation of exercise. Intestinal protein loss (rep..

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