Journal article

A meta-analysis of quality of life for abdominoperineal excision of rectum versus anterior resection for rectal cancer

Julie A Cornish, Henry S Tilney, Alexander G Heriot, Ian C Lavery, Victor W Fazio, Paris P Tekkis

ANNALS OF SURGICAL ONCOLOGY | SPRINGER | Published : 2007

Abstract

BACKGROUND: Avoiding a permanent stoma following rectal cancer excision is believed to improve quality of life (QoL), but evidence from comparative studies is contradictory. The aim of this study was to compare QoL following abdominoperineal excision of rectum (APER) with that after anterior resection (AR) in patients with rectal cancer. METHODS: A literature search was performed to identify studies published between 1966 and 2006 comparing values of QoL following APER and AR. Random-effect meta-analysis was used to combine the data. Sensitivity analyses were performed for larger studies, those of higher quality and those using self-administered QoL questionnaires. RESULTS: The outcomes for ..

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