Journal article

Carboxymethylated cage amines: Coordination and lactamization

PS Donnelly, JM Harrowfield, BW Skelton, AH White

INORGANIC CHEMISTRY | AMER CHEMICAL SOC | Published : 2001

Abstract

Depending upon the position and degree of substitution, carboxymethyl derivatives of cage amines of the "sarcophagine" (3,6,10,13,16,19-hexaazabicyclo[6.6.6]icosane) type vary considerably in the stability of their lactamized forms. For 1,8-diamino-3-carboxymethylsarcophagine, L(1), only indirect evidence for some involvement of a lactamized form of its Ni(II) complex has been obtained. Crystal structure determinations for [Cu(H(2)L(1))](NO(3))(3.5)Cl(0.5) x 2.5H(2)O and [Ni(HL(1))]Cl(3) x 3H(2)O show distorted octahedral coordination of all six endocyclic N-donor atoms in both cases. For related diaminosarcophagine derivatives with either two (1,8; L(2)) or three (1,1,8; L(3)) carboxymethyl..

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University of Melbourne Researchers