Journal article

Mammographic densities during the menopausal transition: a longitudinal study of Australian-born women

Janet R Guthrie, Roger L Milne, John L Hopper, Jennifer Cawson, Lorraine Dennerstein, Henry G Burger

MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY | LIPPINCOTT WILLIAMS & WILKINS | Published : 2007

Abstract

OBJECTIVE: The objective of this study was to investigate hormonal and other factors associated with mammographic density during the menopausal transition and in postmenopause. DESIGN: Mammograms were obtained from 252 participants in the Melbourne Women's Midlife Health Project-a longitudinal population-based study that included annual interviews, blood collection, and physical measurements; 869 original films of the right craniocaudal view were digitized. Total area of the breast and the area of dense tissue were measured, and the percentage of mammographically dense tissue (PMD) was calculated. Data were analyzed using time-series regression models. RESULTS: Of the 252 women, 87% had more..

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