Journal article

Right parietal dysfunction in children with attention deficit hyperactivity disorder, combined type: a functional MRI study

A Vance, TJ Silk, M Casey, NJ Rinehart, JL Bradshaw, MA Bellgrove, R Cunnington

MOLECULAR PSYCHIATRY | NATURE PUBLISHING GROUP | Published : 2007

Abstract

Attention deficit hyperactivity disorder, combined type (ADHD-CT) is associated with spatial working memory deficits. These deficits are known to be subserved by dysfunction of neural circuits involving right prefrontal, striatal and parietal brain regions. This study determines whether decreased right prefrontal, striatal and parietal activation with a mental rotation task shown in adolescents with ADHD-CT is also evident in children with ADHD-CT. A cross-sectional study of 12 pre-pubertal, right-handed, 8-12-year-old boys with ADHD-CT and 12 pre-pubertal, right-handed, performance IQ-matched, 8-12-year-old healthy boys, recruited from local primary schools, was completed. Participants unde..

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