Journal article

Aortic distensibility and retinal arteriolar narrowing - The multi-ethnic study of atherosclerosis

Ning Cheung, A Richey Sharrett, Ronald Klein, Michael H Criqui, Amirul Islam, Katarzyna J Macura, Mary Frances Cotch, Barbara EK Klein, Tien Y Wong

HYPERTENSION | LIPPINCOTT WILLIAMS & WILKINS | Published : 2007

Abstract

Increased aortic stiffness and retinal arteriolar narrowing are subclinical vascular effects of chronic hypertension and predict future cardiovascular events. The relationship between these 2 vascular measures is uncertain and is examined in the Multi-Ethnic Study of Atherosclerosis. This cross-sectional analysis involves 3425 participants (aged 45 to 85 years) free of clinical cardiovascular disease. Retinal vascular caliber was quantified from digital retinal photographs using standardized protocols. Aortic distensibility was determined from chest MRI. After controlling for age, squared age, gender, race, study center, height, weight, heart rate, cigarette smoking, past and current systoli..

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