Journal article

The impact of predictive genetic testing for hereditary nonpolyposis colorectal cancer: three years after testing

Veronica R Collins, Bettina Meiser, Obioha C Ukoumunne, Clara Gaff, D James St John, Jane L Halliday

GENETICS IN MEDICINE | LIPPINCOTT WILLIAMS & WILKINS | Published : 2007

Abstract

BACKGROUND: To fully assess predictive genetic testing programs, it is important to assess outcomes over periods of time longer than the 1-year follow-up reported in the literature. METHODS: We conducted a 3-year study of individuals who received predictive genetic test results for previously identified familial mutations in Australian Familial Cancer Clinics. Questionnaires were sent before attendance at the familial cancer clinic and 2 weeks, 4 months, 1 year, and 3 years after receiving test results. Psychological measures were included each time, and preventive behaviors were assessed at baseline and 1 and 3 years. Psychological measures were adjusted for age, gender, and baseline score...

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