Journal article
Linkage replication of the MYP12 locus in common myopia
Christine Y Chen, Jim Stankovich, Katrina J Scurrah, Pam Garoufalis, Mohamed Dirani, Kelly K Pertile, Andrea J Richardson, Paul N Baird
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE | ASSOC RESEARCH VISION OPHTHALMOLOGY INC | Published : 2007
DOI: 10.1167/iovs.06-1188
Abstract
PURPOSE: Myopia is a common disorder with a large public health impact. Although 12 myopia loci have been reported and heterogeneity for high myopia loci have been demonstrated, replication of high-myopia loci with a common myopia phenotype has not been successful. This study reports the successful replication of MYP12 in three large, multigenerational families with autosomal dominant (AD) common myopia (spherical equivalent [SphE] View full abstract