A diffusion and T-2 relaxation MRI study of the ovine lumbar intervertebral disc under compression in vitro
SC Drew, P Silva, S Crozier, MJ Pearcy
PHYSICS IN MEDICINE AND BIOLOGY | IOP PUBLISHING LTD | Published : 2004
The ovine lumbar intervertebral disc is a useful model for the human lumbar disc. We present preliminary estimates of diffusion coefficients and T2 relaxation times in a pilot MRI study of the ovine lumbar intervertebral disc during uniaxial compression in vitro, and identify factors that hamper the ability to accurately monitor the temporal evolution of the effective diffusion tensor at high spatial resolution.