Journal article

CoMFA analysis of the human beta(1)-adrenoceptor binding affinity of a series of phenoxypropanolamines

SN Louis, LA Rezmann-Vitti, TL Nero, D Iakovidis, GP Jackman, WJ Louis

European Journal of Medicinal Chemistry | ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER | Published : 2002

DOI: 10.1016/S0223-5234(01)01315-0

Grants

Awarded by NIMH NIH HHS

Awarded by NATIONAL INSTITUTE OF MENTAL HEALTH

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Keywords

Science & Technology
Animals
Receptors, Adrenergic, Beta-1
Life Sciences & Biomedicine
Cdna
Models, Molecular
Quantitative Structure-Activity Relationships
Propanolamines
Beta-Adrenoceptor Antagonists
Humans
Adrenergic Beta-1 Receptor Antagonists
Pharmacology & Pharmacy
Heart Atria
Antagonist
Beta-3-Adrenergic Receptor
Cricetinae
Cho Cells
Molecular Structure
Phenoxypropanolamines
Structure-Activity Relationship
Rats
Comparative Molecular Field Analysis
Chemistry, Medicinal
Human Beta 1-Adrenoceptors