Journal article

Omega-3 fatty acids supplementation in children with autism: A double-blind randomized, placebo-controlled pilot study

G Paul Amminger, Gregor E Berger, Miriam R Schaefer, Claudia Klier, Max H Friedrich, Martha Feucht

BIOLOGICAL PSYCHIATRY | ELSEVIER SCIENCE INC | Published : 2007

Abstract

BACKGROUND: There is increasing evidence that fatty acid deficiencies or imbalances may contribute to childhood neurodevelopmental disorders. METHODS: We conducted a randomized, double-blind, placebo-controlled 6-week pilot trial investigating the effects of 1.5 g/d of omega-3 fatty acids (.84 g/d eicosapentaenoic acid, .7 g/d docosahexaenoic acid) supplementation in 13 children (aged 5 to 17 years) with autistic disorders accompanied by severe tantrums, aggression, or self-injurious behavior. The outcome measure was the Aberrant Behavior Checklist (ABC) at 6 weeks. RESULTS: We observed an advantage of omega-3 fatty acids compared with placebo for hyperactivity and stereotypy, each with a la..

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