Journal article

Embryonic factors affecting outcome from single cryopreserved embryo transfer

David H Edgar, Janell Archer, John McBain, Harold Bourne

REPRODUCTIVE BIOMEDICINE ONLINE | ELSEVIER SCI LTD | Published : 2007

Abstract

Multiple pregnancy minimization by single embryo transfer is becoming more prevalent, but is less common in the case of cryopreserved embryos. This study defines embryonic characteristics in single cryopreserved embryo transfers associated with success rates equivalent to those achieved when transferring two cryopreserved embryos. In a retrospective analysis of 6916 cryopreserved day-2 embryo transfer procedures, transfer of two cryopreserved embryos resulted in higher clinical pregnancy rates when compared with transfer of a single thawed embryo but was also associated with elevated multiple pregnancy rates (26.7% in women under 36). Optimal outcome (implantation rate of 30.9%) from single ..

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