Journal article

Efficacy and safety of multiple intravitreal triamcinolone injections for refractory diabetic macular oedema

Mark C Gillies, FM Amirul Islam, Meidong Zhu, Jorgen Larsson, Tien Y Wong

BRITISH JOURNAL OF OPHTHALMOLOGY | BMJ PUBLISHING GROUP | Published : 2007

Abstract

AIM: The efficacy and safety of repeated injections of intravitreal triamcinolone (IVTA) for diabetic macular oedema is unclear, with results of previous reports conflicting. METHODS: This is a prospective, observational case series of 27 eyes receiving IVTA for diabetic macular oedema. LogMAR visual acuity (VA) and central macular thickness (CMT) were measured at baseline and in 3 to 6 monthly intervals for up to 24 months, then correlated with the number of IVTA injections given. RESULTS: One IVTA injection was required in 6 (18%) eyes, 2 in 8 (24%) eyes, 3 in 13 (39%) eyes and 4-5 in 6 (18%) eyes. VA improved in all patients, but neither the final improvement in VA nor the absolute improv..

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