Journal article

How significant is a family history of glaucoma? Experience from the Glaucoma Inheritance Study in Tasmania

Catherine M Green, Lisa S Kearns, Johnny Wu, Julie M Barbour, Robyn M Wilkinson, Maree A Ring, Jamie E Craig, Tiffany L Wong, Alex W Hewitt, David A Mackey

CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY | BLACKWELL PUBLISHING | Published : 2007

Abstract

PURPOSE: To determine what proportion of primary open angle glaucoma (POAG) in Tasmania, Australia is familial. METHODS: Between 1994 and 1996 an audit of Tasmanian patients diagnosed with glaucoma was performed. Identified probands along with their family members were invited to participate. Family history of POAG was noted and pedigrees constructed. Each participant underwent a detailed examination, including visual acuity, intraocular pressure measurement, gonioscopy, optic disc assessment and visual field testing. Participants were classified as normal, suspect or POAG. Data from 467 participants in the Twins Eye Study in Tasmania (TEST) were used as a reference for the general populatio..

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