Journal article

The Magpie Trial: a randomised trial comparing magnesium sulphate with placebo for pre-eclampsia. Outcome for women at 2 years

Lelia Duley, Barbara Farrell, Nina Armstrong, Patsy Spark, Barbara Roberts, Rebecca Smyth, Mary Tivnan, Anna Laws, Noelene Corfield, Annette Salter, Lisa Thorn, Douglas Altman, Ly-Mee Yu, Edgardo Abalos, Berenise Carroli, Lucrecia Dellepiane, Marina Duarte, Hebe Fernandez, Daniel Giordano, Mike Clarke Show all

BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY | WILEY | Published : 2007

Abstract

OBJECTIVE: The aim of this study was to assess long-term effects for women following the use of magnesium sulphate for pre-eclampsia. DESIGN: Assessment at 2-3 years after delivery for women recruited to the Magpie Trial (recruitment in 1998-2001, ISRCTN 86938761), which compared magnesium sulphate with placebo for pre-eclampsia. SETTING: Follow up after discharge from hospital at 125 centres in 19 countries across five continents. POPULATION: A total of 7927 women were randomised at the follow-up centres. Of these women, 2544 were not included for logistic reasons and 601 excluded (109 at a centre where <20% of women were contacted, 466 discharged without a surviving child and 26 opted out)..

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