Journal article

Circadian rhythm of blood glucose values in critically ill patients

Moritoki Egi, Rinaldo Bellomo, Edward Stachowski, Craig J French, Graeme Hart, Peter Stow

CRITICAL CARE MEDICINE | LIPPINCOTT WILLIAMS & WILKINS | Published : 2007

Abstract

OBJECTIVE: To test whether there is a circadian rhythm of blood glucose control in critically ill patients and whether morning blood glucose is an accurate surrogate of overall blood glucose control. DESIGN: Retrospective multiple-center observational study. SETTING: Intensive care units of three tertiary hospitals and one affiliated private hospital. PATIENTS: Cohort of 8,307 consecutive critically ill patients. INTERVENTIONS: Extraction of blood glucose values from electronically stored measurements. Extraction of demographic and outcome data from unit and hospital databases. Statistical assessment of variations in blood glucose control over each 24-hr cycle. MEASUREMENTS AND MAIN RESULTS:..

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