Journal article
Noninferiority of antibody response to human papillomavirus type 16 in subjects vaccinated with monovalent and quadrivalent L1 virus-like particle vaccines
SM Garland, M Steben, M Hernandez-Avila, LA Koutsky, CM Wheeler, G Perez, DM Harper, S Leodolter, GWK Tang, DG Ferris, MT Esser, SC Vuocolo, M Nelson, R Railkar, C Sattler, E Barr
Clinical and Vaccine Immunology | Published : 2007
DOI: 10.1128/CVI.00478-06
Abstract
The incorporation of multiple antigens into a single human papillomavirus (HPV) vaccine may induce immune interference. To evaluate whether interference occurs when HPV type 16 (HPV16) virus-like particles are combined in a multivalent vaccine, we conducted a study to evaluate anti-HPV16 responses among subjects receiving three-dose regimens of either a monovalent HPV16 vaccine or a quadrivalent HPV (types 6, 11, 16, and 18) vaccine. Copyright © 2007, American Society for Microbiology. All Rights Reserved.