Journal article

Magnetization transfer effects on the efficiency of flow-driven adiabatic fast passage inversion of arterial blood

Luis Hernandez-Garcia, David P Lewis, Bradford Moffat, Craig A Branch

NMR IN BIOMEDICINE | WILEY | Published : 2007

Abstract

Continuous arterial spin labeling experiments typically use flow-driven adiabatic fast passage inversion of the arterial blood water protons. In this article, we measure the effect of magnetization transfer in blood and how it affects the inversion label. We use modified Bloch equations to model flow-driven adiabatic inversion in the presence of magnetization transfer in blood flowing at velocities from 1 to 30 cm/s in order to explain our findings. Magnetization transfer results in a reduction of the inversion efficiency at the inversion plane of up to 3.65% in the range of velocities examined, as well as faster relaxation of the arterial label in continuous labeling experiments. The two ef..

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University of Melbourne Researchers