Journal article
Interleukin-6 expression after infectious bronchitis virus infection in chickens
Manija Asif, John W Lowenthal, Mark E Ford, Karel A Schat, Wayne G Kimpton, Andrew GD Bean
VIRAL IMMUNOLOGY | MARY ANN LIEBERT, INC | Published : 2007
Abstract
Viral infections in chickens pose a major health threat to the poultry industry. Infectious bronchitis virus (IBV) usually causes respiratory disease; however, the disease severity is influenced by the genotype of the chicken and the IBV strain involved. Nephropathogenic strains of IBV, such as the Australian T strain, can cause high mortalities due to kidney failure characterized by mononuclear cell infiltration and inflammation. In a previous study, a line of specific pathogen-free chickens, the S-line, was shown to be susceptible to high mortalities from IBV infection. The cause of these high mortalities is unknown but it is suspected that differential cytokine expression may play a role...
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