Assembling DNA into advanced materials: From nanostructured films to Biosensing and delivery systems

Abstract

The past decade has witnessed a rapid expansion in the design and assembly of engineered materials for biological applications. However, such applications place limitations on the molecular building blocks that can be used. Requirements for polymer-based building blocks include biocompatibility, biodegradability, and stimuli-responsive behavior. Many traditional polymers used in materials science are limited in at least one of these areas, so new polymers need to be explored. As we outline here, DNA is one such polymer that shows promise in developing the next generation of 'smart' materials for biomedical and diagnostic applications. © 2007 WILEY-VCH Verlag GmbH & Co. KGaA,.