Journal article
The Claisen rearrangement approach to fused bicyclic medium-ring oxacycles
Jonathan W Burton, Edward A Anderson, Paul T O'Sullivan, Ian Collins, John E Davies, Andrew D Bond, Neil Feeder, Andrew B Holmes
ORGANIC & BIOMOLECULAR CHEMISTRY | ROYAL SOC CHEMISTRY | Published : 2008
DOI: 10.1039/b715354f
Abstract
The synthesis of five fused-bicyclic medium-ring lactones carrying identical ring-fusion to that in the polyether toxins is described using an enolate hydroxylation, intramolecular hydrosilation, Claisen rearrangement sequence.