Journal article

Group A streptococcal infections in children

Andrew C Steer, Margaret H Danchin, Jonathan R Carapetis

JOURNAL OF PAEDIATRICS AND CHILD HEALTH | WILEY | Published : 2007

Abstract

The group A streptococcus causes the widest range of disease in humans of all bacterial pathogens. Group A streptococcal diseases are more common in children than adults with diseases ranging from pharyngitis and impetigo to invasive infections and the post-streptococcal sequelae--acute rheumatic fever and acute post-streptococcal glomerulonephritis. The global burden of severe group A streptococcal disease is concentrated largely in developing countries and Indigenous populations such as Aboriginal Australians. Control of group A streptococcal disease is poor in these settings and the need for a vaccine has been argued. With an ever-increasing understanding of the group A streptococcus at a..

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