Journal article

Medium term follow-up of a randomized controlled trial of interventions for young people at ultra high risk of psychosis

Lisa J Phillips, Patrick D McGorry, Hok Pan Yuen, Janine Ward, Kerri Donovan, Daniel Kelly, Shona M Francey, Alison R Yung

SCHIZOPHRENIA RESEARCH | ELSEVIER SCIENCE BV | Published : 2007

Abstract

Valid criteria to identify young people who are believed to be at ultra high risk (UHR) of developing a psychotic episode were developed over the last decade. The first randomized controlled trial of treatment in a UHR cohort indicated that specific pharmacotherapy and psychotherapy delayed onset of disorder, and possibly reduced incidence. This paper reports results of follow-up of that trial. 41 of the 59 (69.5%) participants in the original study agreed to follow-up. No differences were found in transition rate, level of symptomatology or functioning between participants who received a combination of psychological treatment and anti-psychotic medication compared to those who received supp..

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