Journal article

Cognitive testing in early-phase clinical trials: Development of a rapid computerized test battery and application in a simulated Phase I study

Alex Collie, Amanda Darekar, Georges Weissgerber, Melvin K Toh, Peter J Snyder, Paul Maruff, John P Huggins

Contemporary Clinical Trials | ELSEVIER SCIENCE INC | Published : 2007

DOI: 10.1016/j.cct.2006.10.010

University of Melbourne Researchers

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Keywords

Psychometrics
Pharmacology & Pharmacy
Sensitivity and Specificity
Diagnosis, Computer-Assisted
Clinical Trial
Neuropsychological Tests
Impairment
Adolescent
Middle Aged
Phase I
Cogstate
Psychomotor
Memory
Adverse Event
Life Sciences & Biomedicine
Research Design
Neuropsychological Test-Performance
Flumazenil
Cognition
Multicenter Studies As Topic
Adult
Dose-Response Relationship, Drug
Double-Blind Method
Humans
Male
Midazolam
Science & Technology
Pharmacokinetics
Clinical Trials, Phase I As Topic
Recovery
Medicine, Research & Experimental
Hypnotics and Sedatives
Healthy Elderly Volunteers
Brain
Research & Experimental Medicine