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Journal article

Disparity of histone deacetylase inhibition on repair of radiation-induced DNA damage on euchromatin and constitutive heterochromatin compartments

TC Karagiannis, H Kn, A El-Osta

Oncogene | NATURE PUBLISHING GROUP | Published : 2007

DOI: 10.1038/sj.onc.1210174

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Tom Karagiannis Author Clinical Pathology

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TARGETING 1241 TO THE DNA OF TUMOURS FOR PET IMAGING AND AUGER-RADIOTHERAPY

The aim of this project is to develop a new method of targeting radioactivity to tumours, for detection and treatment, using a radioactive e..

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Keywords

Photolyase
Histone Deacetylase Inhibitors
Hydroxamic Acids
Cell Biology
Enhancement
Heterochromatin
In-Vivo
Biochemistry & Molecular Biology
Oncology
Histone Acetylation
Dna, Neoplasm
Human-Cells
Acetylation
Euchromatin
Trichostatin a
Chip
Methylation
K562 Cells
Gamma H2ax
Radiation Sensitivity
Dna Repair
Caspases
Humans
Tumor Radiosensitivity
Blotting, Western
Chromatin Immunoprecipitation
Saccharomyces-Cerevisiae
Dose-Response Relationship, Drug
Dna Breaks, Double-Stranded
Active Chromatin
Time Factors
Life Sciences & Biomedicine
Nucleotide Excision-Repair
Histone Deacetylases
Enzyme Inhibitors
Cell Cycle
Dna Damage
Hdac Inhibitor
Cell Survival
Genetics & Heredity
Science & Technology
Cancer

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