Journal article

Relation between fasting glucose and retinopathy for diagnosis of diabetes: three population-based cross-sectional studies

Tien Y Wong, Gerald Liew, Robyn J Tapp, Maria Ines Schmidt, Jie Jin Wang, Paul Mitchell, Ronald Klein, Barbara EK Klein, Paul Zimmet, Jonathan Shaw



BACKGROUND: The WHO and American Diabetes Association criteria for diagnosing diabetes mellitus assume the presence of a glycaemic threshold with high sensitivity for identifying retinopathy. However, this assumption is based on data from three previous studies that had important limitations in detecting retinopathy. We aimed to provide updated data for the relation between fasting plasma glucose (FPG) and retinopathy, and to assess the diagnostic accuracy of current FPG thresholds in identifying both prevalent and incident retinopathy. METHODS: We examined the data from three cross-sectional adult populations: those in the Blue Mountains Eye Study (BMES, Australia, n=3162), the Australian D..

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