Journal article

The relationship between birthweight and early age-related maculopathy: The atherosclerosis risk in communities study

Gerald Liew, Jie Jin Wang, Ronald Klein, Bruce B Duncan, Frederick Brancati, Hsin-Chieh Yeh, Tien Y Wong

OPHTHALMIC EPIDEMIOLOGY | INFORMA HEALTHCARE | Published : 2008

Abstract

PURPOSE: Birthweight is a marker of fetal growth, and has been linked to future risk of chronic diseases in adults. We examined the association between birthweight and age-related maculopathy (ARM). METHODS: We studied 9730 adults from the population-based Atherosclerosis Risk in Communities study, of whom 4744 reported their exact birthweight and an additional 4986 provided categorical birthweight data (low, medium or high). We graded retinal photographs for presence of ARM using a modification of the Wisconsin ARM Grading System. RESULTS: Early ARM was present in 479 (4.9%) adults. Among persons with exact birthweight data, there was no association between birthweight and early ARM (OR 1.1..

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