Journal article

Retinal signs and stroke - Revisiting the link between the eye and brain

Michelle L Baker, Peter J Hand, Jie Jin Wang, Tien Y Wong

Stroke | LIPPINCOTT WILLIAMS & WILKINS | Published : 2008


BACKGROUND AND PURPOSE: The retinal and cerebral vasculature share similar anatomic, physiological, and embryological characteristics. We reviewed the literature, focusing particularly on recent population-based studies, to examine the relationship between retinal signs and stroke. Summary of Review- Hypertensive retinopathy signs (eg, focal retinal arteriolar narrowing, arterio-venous nicking) were associated with prevalent stroke, incident stroke, and stroke mortality, independent of blood pressure and other cerebrovascular risk factors. Diabetic retinopathy signs (eg, microaneurysms, hard exudates) were similarly associated with incident stroke and stroke mortality. Retinal arteriolar emb..

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