Ethnic variability in retinal vessel caliber: A potential source of measurement error from ocular pigmentation? - The Sydney childhood eye study

Abstract

PURPOSE: To describe the effects of ethnicity and iris color on measurement of retinal vascular caliber. METHODS: The Sydney Childhood Eye Study (SCES) examined 1740 6-year-old children from 34 randomly selected Sydney schools during 2003 and 2004. Retinal arteriolar and venular calibers (central retinal arteriolar [CRAE] and central retinal venular [CRVE] equivalents) were measured from retinal photographs by a standardized computer-assisted METHOD: Associations of retinal vascular caliber with ethnicity and iris color were analyzed. RESULTS: Of the total participants, 1612 (92.6%) had gradable retinal photographs. CRAE and CRVE were normally distributed, with means (SD) of 163.2 (14.0) and..